BACKGROUND: This study aims to explore the psychosocial factors related to the severity of pain in patients with non-cardiac chest pain (NCCP), providing insights to support more comprehensive and targeted management strategies. METHODS: This cross-sectional study was conducted at two university-affiliated hospitals. Patients diagnosed with NCCP, based on physical examination and angiographic findings, completed questionnaires assessing type D personality, cardiac anxiety, fear of bodily sensations, somatization, depression, and pain severity. Univariate and multiple logistic regression analyses were conducted to identify factors influencing pain severity levels. RESULTS: A total of 156 males and 204 females, with a mean age of 55. 76 ± 12. 83 years, were divided into low-pain (N = 182) and high-pain (N = 178) groups. Higher education and being female were significantly associated with greater pain severity. Depression, type D personality, somatization, and cardiac anxiety were significantly correlated with pain severity. Multiple logistic regression analysis indicated that self-rated health (OR,: 2. 14,95% CI.: 1. 18-3. 90), depression (OR-11. 15,95% CI-: 1. 09-1. 22), type D personality (OR-: 1. 90,95% CI-: 1. 06-3. 41), somatization (OR-: 1. 03,95% CI-: 1. 01-1. 06), and fear of bodily sensation (OR-: 1. 90,95% CI-: 1. 06-3. 41), were all associated with pain severity. CONCLUSION: This study concluded that type D personality, fear of bodily sensations, depression, somatization, cardiac anxiety, and poor self-rated health were associated with increased NCCP severity. By controlling the disease and managing related pain earlier, more coherent treatment strategies can be implemented, ultimately improving patients’ quality of life.